What is the role of leukotriene modifiers in treating allergic rhinitis?

• A. They increase mucus production
• B. They reduce inflammation and mucus production in response to allergens
• C. They stimulate the immune response
• D. They are used only for chronic obstructive pulmonary disease

Answer: (B)

Leukotriene modifiers work by blocking leukotriene pathways, which are inflammatory signals released when allergens trigger immune cells. In allergic rhinitis, leukotrienes contribute to nasal mucosal swelling and increased mucus production. By inhibiting their action, these drugs lessen the inflammatory response and reduce mucus production in reaction to allergens, helping relieve nasal symptoms. They’re not the first-line therapy for allergic rhinitis and are often used as add-on treatment, especially in patients with concurrent asthma; they aren’t immunostimulants and are not limited to COPD management.